Long COVID Studies & Clinical Trials in Canada
Research you can take part in, from short online questionnaires to clinical trials, for people in Canada living with long COVID, ME/CFS, POTS and other forms of dysautonomia, or Lyme disease.
- 13 listings
- 3 recruiting now
- Sept 2026 last reviewed
Showing 13 of 13 listings
New studies
The latest long COVID research looking for volunteers.
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Online Long COVID Study on Language Processing
A University of York study on how long COVID affects language. Short questions followed by language tasks, all online, in 15 minutes or less. Open to native English speakers aged 18 and over, with or without long COVID.
See study details: Online long COVID study on language processing -
Taurine and Blood Vessel Health in Long COVID
York University is testing whether 12 weeks of taurine improves blood vessel function and dizziness or faintness when standing. Run by Dr. Heather Edgell and Dr. Andrea Josse at the Keele Campus in Toronto.
See study details: Taurine study for long COVID in Toronto
All studies and research programs
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Online ~ AnywhereRecruiting
Long COVID and Language Processing
University of York. A 15 minute online questionnaire and language tasks. Ages 18 and over, native English speakers, with or without long COVID.
See study details for the language processing study -
Ontario ~ TorontoRecruiting
Taurine Supplement Study
York University is testing a 12 week taurine supplement for blood vessel function and dizziness on standing in people with long COVID.
See study details for the taurine study -
Quebec ~ Montreal & SherbrookeEnrolling
LC-REVITALIZE Clinical Trial
An international trial testing whether upadacitinib, an existing medication, can ease long COVID symptoms. Canadian sites are in Montreal and Sherbrooke.
See trial details for LC-REVITALIZE -
Canada ~ Led from TorontoRecruiting
RECLAIM Long COVID Trial
A national University Health Network trial now enrolling adults 18+ in Canada with symptoms lasting more than 3 months. Current arms test taurine, hyperbaric oxygen and the Hi-OxSR breathing device. Contact reclaim@uhn.ca or 1-866-673-2524.
See current trials for the RECLAIM trial (opens in a new tab) -
Alberta ~ CalgaryRecruiting
Brain Fog in Long COVID and POTS
University of Calgary study of thinking and memory in people with POTS or long COVID brain fog, with heart rate and blood pressure tests lying and standing. Ages 18 to 60, including healthy volunteers. Email autonomic.research@ucalgary.ca.
See study details for the brain fog study (opens in a new tab) -
British Columbia ~ OnlineRecruiting
Long COVID Blood Test Research
University of British Columbia researchers want to hear from adults with long COVID to help develop a blood test for diagnosis. A short questionnaire and a 30 minute interview by Zoom or in person, with compensation. Email estefania.espin@hli.ubc.ca.
Read the study poster for the UBC biomarker study (opens in a new tab) -
Prairie provinces ~ OnlineRecruiting
Self Care for Long COVID Fatigue
University of Saskatchewan study for people aged 30 to 55 in Alberta, Saskatchewan or Manitoba with post COVID fatigue and mental health concerns. A survey and two video sessions, with a $50 honorarium. Email kelly.hall@usask.ca.
Read the study poster for the fatigue self care study (opens in a new tab) -
Canada ~ OnlineRecruiting
Person and Family Centred Long COVID Care
University of Toronto interviews with adults living with long COVID, family caregivers and healthcare providers across Canada about care planning. One interview by phone or video, about an hour. Email Caregiving.Study@utoronto.ca.
Read the study poster for the family centred care study (opens in a new tab) -
Ontario ~ TorontoRecruiting
Long COVID Gait and Balance Study
Researchers at the University of Toronto and Toronto Rehab (UHN) are studying how long COVID affects walking and balance. Email janna.marvyn@uhn.ca for details.
See study details for the gait and balance study (opens in a new tab) -
Canada ~ OnlineRecruiting
StudyME Research Registry
Open Medicine Foundation Canada’s free registry matches people with ME/CFS, long COVID, fibromyalgia and related illnesses, and healthy volunteers, with new studies by email. Sign up takes 5 minutes.
Join the registry for StudyME (opens in a new tab) -
CanadaRecruiting
University of Guelph Tick Study
The G. Magnotta Lyme Disease Research Lab at the University of Guelph is collecting blacklegged ticks removed from people, pets or livestock in Canada to study Lyme disease and other tick infections. Fill in the online form to donate a tick, or email gmlstudy@uoguelph.ca.
Donate a tick for the Guelph tick study (opens in a new tab) -
Canada ~ Online
Long COVID Citizen Science Survey
An anonymous online survey about your long COVID symptoms and how they affect you. You can compare your answers with others to help guide research.
Visit website for the citizen science survey (opens in a new tab) -
Canada
Long COVID Web
A CIHR funded national network of scientists, clinicians and people with lived experience. Lists research engagement and study recruitment across Canada.
Visit website for Long COVID Web (opens in a new tab) -
British Columbia
Post-COVID-19 Care Network Research
BC’s Post-COVID-19 Interdisciplinary Clinical Care Network lists long COVID research you can take part in, including the RECLAIM trial, a mental health study and smell loss research at the University of Victoria.
Visit website for PHSA post COVID research (opens in a new tab) -
British Columbia
REACH BC
A free platform from Clinical Trials BC that matches volunteers with health research studies across the province and sends study alerts.
Visit website for REACH BC (opens in a new tab) -
Alberta ~ CalgaryRecruiting
Calgary POTS Studies
The Calgary Autonomic Investigation lab is recruiting adults 18+ for several POTS studies, including the CASA-POTS salt trial, adrenergic antibodies in POTS, and chest pain and heart health in POTS. Email autonomic.research@ucalgary.ca.
See current studies for the Calgary POTS studies (opens in a new tab) -
Alberta ~ Calgary
PaCER
Patient and Community Engagement Research at the University of Calgary trains people with lived health experience to take part in research as partners.
Visit website for PaCER (opens in a new tab) -
SaskatchewanRecruiting
Lung Saskatchewan Research Studies
Lung Saskatchewan lists research open to volunteers, including a long COVID survey on virtual care and a study of ongoing shortness of breath after COVID-19.
Visit website for Lung Saskatchewan research (opens in a new tab) -
Saskatchewan
Saskatchewan Centre for Patient-Oriented Research
SCPOR brings patients into health research as partners, working alongside researchers, clinicians and community groups.
Visit website for SCPOR (opens in a new tab) -
Canada
Health Canada Clinical Trial Search
Health Canada’s database of approved drug trials in Canada. Search by condition, such as long COVID, ME/CFS, POTS or Lyme disease, to see status, sites and contacts.
Search trials for Health Canada trials (opens in a new tab) -
Canada
ICanCME Research Network
Canada’s ME/CFS research network, founded with people with ME. Membership is free for people with ME and families who want news on Canadian ME research and chances to get involved.
Join the network for ICanCME (opens in a new tab) -
Canada
eTick
Submit a photo of a tick found on you, a pet or outdoors. Experts identify it for free, and the data help track Lyme disease risk across Canada.
Submit a tick for eTick (opens in a new tab) -
International ~ Online
MyLymeData Patient Registry
A large Lyme disease patient registry run by LymeDisease.org. It focuses on infections acquired in the US, but people in Canada can register and record where they were bitten.
Visit website for MyLymeData (opens in a new tab)
No matching studies
Try a different word, or clear your filters to see every listing.
You can also join a research registry to be matched to new studies, or get new studies by email.
Questions to ask before joining a study
Taking part should never make you sicker. These questions help you decide if a study is a good fit.
- Is it approved?Look for research ethics board approval, usually listed on the study page or consent form.
- How much energy will it take?Ask about travel, visit length and any exercise testing, especially if you have post exertional malaise.
- Can I do it from home?Many surveys and some studies are fully online. Ask if remote options or breaks are available.
- Can I stop at any time?You can always withdraw. Your care should never depend on taking part.
Earlier studies I have shared
These may now be closed. Contact the research team to check.
- Establishing a national long COVID data setUniversity of Saskatchewan ~ May 2024
- CAMH brain health after COVID-19 studyToronto ~ March 2023
- COVID-19 cognitive effects MRI studyDalhousie University, Halifax ~ March 2023
Frequently asked questions
How do I find long COVID studies in Canada?
Use the filters above to see studies by province or type. For more, Health Canada’s clinical trial search lists approved drug trials across Canada, Long COVID Web lists long COVID research, and REACH BC matches volunteers with studies in British Columbia.
Are there studies for ME/CFS, POTS or Lyme disease in Canada?
Yes. Use the Condition filter above. The Calgary Autonomic Investigation lab runs several POTS studies, and Open Medicine Foundation Canada’s StudyME registry matches people with ME/CFS and long COVID to new studies. Lyme disease studies open to patients are rarer in Canada, but you can help tick research through eTick or the University of Guelph, and search Health Canada’s trial database for new trials.
Can I take part in a long COVID study online?
Yes. Some studies and surveys are completed entirely online, like the University of York language processing study and the long COVID citizen science survey. Select “Online” above to see them.
Are there long COVID clinical trials in Canada?
Yes. The LC-REVITALIZE trial is testing upadacitinib in Montreal and Sherbrooke, Quebec, and York University in Toronto is testing a taurine supplement. Select “Clinical trials” above to see them.
Is it safe to join a study if I have post exertional malaise?
Ask the research team what the study involves before you agree. Studies with travel, long visits or exercise testing can trigger a crash. You can ask for breaks, remote options or to withdraw at any time.
How can I get my study listed here?
Email admin@longcovidresourcescanada.ca with your study details, ethics approval and recruitment poster. I can feature it on this page and in the newsletter.
Running a long COVID study?
I share research opportunities with the long COVID community on this page and in the newsletter.
Please note: Listing a study here is not an endorsement, and nothing on this page is medical advice. Study details can change, so always confirm eligibility and status with the research team.
